Welcome to CyMoBase.

A database for cytoskeletal and motor protein sequence information

Acceptance of our analysis of the myosins (September 2007)

Recently, the analysis of the myosin repertoire in eukaryotes has been finished and published.

F. Odronitz & M. Kollmar (2007) Open Access Highly Accessed
Genome Biology 8, R196.

Myosin Tree  Myosin Domains  Myosin Evolution

For a thorough review of the work of Richards and Cavalier-Smith (Nature 2005), and Foth, Goedecke, and Soldati (PNAS 2006) please contact M. Kollmar.

Purpose of the Database

CyMoBase is a database driven web application that is designed to assist researchers investigating structure, function and phylogeny of cytoskeletal and motor proteins during their daily work. [ . . . ]

Usage

The web interface has been designed using the next generation internet features (Web 2.0). [ . . . ]

Limitations

At the moment, CyMoBase only contains protein sequences. [ . . . ]

Note

The domain predictions are based on the profiles of Pfam_fs release 19.0 database containing 8183 hidden markov models. We haven't included the resuls of the updated profiles yet that have been derived from our alignments, as well as coiled-coil and motif predictions. Therefore the domain organisation images will undergo severe changes in the near future.

News

2009-01-01

This is a major update of the web-interface and the myosin data. Several new search modules and result views have been developed and some hundred new myosin and other motor protein sequences added.[ . . . ]

Coming next

Protein projects

Analysis of the kinesins.

New database features

Currently, we are working on an interactive tool that will allow the user to move through the alignment of selected sequences.

On top of the to-do-list also is the inclusion of the updated domain profiles.

Cymobase Content

Proteins12
Sequences4164
Amino Acids6227257
Domains66
Species475
Projects1489
WGS-Projects515
Publications624
link to diark
link to scipio
link to www.motorprotein.de
MPI for biophysical chemistry
    Please wait ...